【病例速览 第23期】加湿器消毒剂相关肺损伤，您知道多少？

专家简介：卜学勇，国防科技大学医院放射科，主要从事CT、普放工作。胸科之窗学术部主管。

Brief Review

In adults, adenovirus pneumonia occurs commonly in immunocompromised hosts including patients who have received organ and bone marrow transplants, whereas in healthy individuals it is rare. 成人腺病毒肺炎通常发生于免疫力低下宿主，包括接受器官与骨髓移植者，因而发生于健康个体罕见。

Adenovirus pneumonia presented with patchy ground-glass opacities with or without consolidation on HRCT in both immunocompromised and immunocompetent patients. 免疫力低下或正常患者腺病毒肺炎HRCT均表现为斑片状GGO，伴或不伴实变。

Ground-glass opacity corresponds histopathologically to areas of acute diffuse alveolar damage comprising interstitial lymphocyte infiltration, intraalveolar hemorrhage, edema and fibrin, type II cell hyperplasia, and hyaline membrane formation. Alveolar lining cells show intranuclear inclusions, which is positive for immunohistochemical staining.

GGO在组织学上对应于急性弥漫性肺泡损伤（DAD）区域，包括肺间质淋巴细胞浸润、肺泡出血、水肿和纤维蛋白沉积，II型肺泡上皮增生与透明膜形成。肺泡衬细胞见免疫组织化学染色阳性的核内包涵体。

From：Korean Society of Thoracic Radiology

http://kstr.radiology.or/weekly/

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